Draft scaffold · replace via Claude Design

Biophilia Genetics

Edit the plant, not the genome's paperwork.

A DNA-free, single-generation genome-editing platform with real freedom to operate — engineering bioenergy crops for energy security and food security at once.

The platform

Direct editing, one generation, no transgenes

An IVF-based system edits directly in the genotype you want — RNP / DNA-free, no transgene integration — in a single generation. It works in maize today and transfers to sorghum, where the gametes are actually easier to extract. Because it sits outside Big Ag's IP thicket, we have genuine freedom to operate. Going DNA-free keeps the regulatory surface small — the EU lifted its gene-editing restrictions in mid-2026.

The wedge

Sorghum as jet fuel

The Department of Energy has funded a sorghum bioenergy program at the University of Nebraska–Lincoln for twelve years. Its high-oil lines are in field testing and engineered to accumulate the 14-carbon fatty-acid precursors of aviation fuel — not commodity seed oil. We leapfrog that investment: our product is the improved sorghum lines themselves, licensed to energy producers. We are not in the refinery business.

4% → 17%
Oil content: field-tested today, engineered target
12 yrs
DOE-funded sorghum bioenergy foundation
1 gen
Multi-allele edits in a single growing generation

The mission

Energy security and food security — one platform

Sorghum is a strong energy wedge: arguably a non-food crop, with oil directed into the vegetative tissue. But the platform is generic. Single-generation, multi-allele editing in the genotype you want is a food-security technology as much as an energy one. We build for both — not sustainability boilerplate, and not energy to the exclusion of food. Build seeds, not bombs.

Funding

SBIR / STTR across four agencies

  • Biophilia Genetics can file on its own for the August and September deadlines.
  • Partnership SBIRs (e.g. germplasm and tropical maize lines) open a second lane, with control retained.
  • Live across DOE, DOD, and NIH — energy security and food security framing.
  • Grant awards can be levered into working capital through receivables-backed lending.